Susan Murphy, Ph.D.
Research Interests:
- Blast-induced Neurotrauma
Past Research:
- Pre-clinical Experimental Therapeutics for Glioblastoma
Education:
- B.S. Chemistry, Macquarie University
- M.S. Chemistry, Macquarie University
- Ph.D. Medicine, University of Sydney
Publications:
Dickerson MR, Bailey ZS, Murphy SF, Urban MJ, VandeVord PJ, Glial Activation in the Thalamus Contributes to Vestibulomotor Deficits Following Blast-Induced Neurotrauma, Front. Neurol, 618, July 15, 2020.
Varghese R, Young S, Pham L, Liang Y, Pridham K, Guo S, Murphy SF, Kelly D, Sheng Z. Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival; Scientific Reports; 8(1) 13621, 2018.
Murphy SF, Varghese RT, Lamouille S, Guo S, Pridham KJ,Kanabur P, Osimani AM, Sharma S, Jourdan J, Rodgers CM, Simonds GR, Gourdie RG, Sheng Z. A Connexin 43 Mimetic Peptide Sensitizes Glioblastoma Cells to Temozolomide, Cancer Research: Jan1:76(1), 139-49, 2016.
Li T, Murphy SF, Kiselev B, Bakshi K, Zhang J, Eltahir A, Zhang Y, Chen Y, Zhu J, Davis R, Madsen L, Morris J, Karolyi D, LaConte S, Sheng Z, Dorn H. A New Interleukin-13 Amino-Coated Gadolinium Metallofullerene Nanoparticle for Targeted MRI Detection of Glioblastoma Tumor Cells; Journal of the American Chemical Society, 137 (24), 7881-8, 2015.
Guo S, Liang Y, Murphy SF, Huang A, Shen H, Sobrado P, Kelly D, Sheng Z. A rapid and high content assay that quantitatively measures autophagy and autophagy flux with potential clinical applications. Authophagy, 11(3), 560-72, 2015.
Sheng Z, Murphy SF, Guo S, Green MR. A diphtheria toxin negative selection in RNA interference screening. Methods Mol Biol. 2014;1176:59-72. doi: 10.1007/978-1-4939-0992-6_6. PubMed PMID: 25030919.
Paris D, Ganey N, Banasiak M, Laporte V, Patel N, Mullan M, Murphy SF, Yee GT, Bachmeier C, Ganey C, Beaulieu-Abdelahad D, Mathura VS, Brem S, Mullan M. Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease. The Journal of neuroscience , 30(34), 11251-8, 2010.
Murphy SF, Davey RA, Gu XQ, Haywood MC, McCann LA, Mather LE, Boyle FM. Enhancement of cisplatin efficacy by thalidomide in a 9L rat glioma model. Journal of Neuro-oncology, 85, 181-189. 2007.
Murphy-Poulton SF, Boyle F, Davey R, Gu S, Mather LE. Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU. Journal of Pharmacy and Pharmacology, 59(1), 105-114, 2007.
Murphy-Poulton SF, Boyle F, Gu XQ, Mather LE. Thalidomide enantiomers: determination in biological samples by HPLC and vancomycin-CSP. Journal of Chromatography B 831, 48-56, 2006.
Murphy-Poulton SF, Vagg RS, Vickery KA, Williams PA. DNA binding of some chiral metallointercalators derived from 9,10-phenenthrenediamine. Metal-Based Drugs, 5(4), 1998.